Chicago's hospital map moved more in the last 20 months than in most decades. Ascension St. Elizabeth closed in February 2025. On March 1, 2025, Prime Healthcare completed its purchase of eight Ascension hospitals in Illinois, including Resurrection and Saint Mary of Nazareth in Chicago, Saint Francis in Evanston, Holy Family in Des Plaines and Saint Joseph in Joliet and Elgin, and said it had offered jobs to substantially all of the hospitals' employees.
Then two safety-net hospitals owned by Resilience Healthcare shut. Weiss Memorial in Uptown closed on August 8, 2025, a day before Medicare was set to end its participation. West Suburban Medical Center in Oak Park stopped emergency, inpatient and clinic care on March 25, 2026, and furloughed staff. In September 2026 the hospitals' landlord reached a settlement to buy out the owner, with Insight Health Systems expected to buy both hospitals. Neither had reopened, Weiss had lost its state hospital license, and Insight said West Suburban could take at least four months to reopen and Weiss longer.
For employers, that means experienced nurses, techs and registration staff from those hospitals have been looking for work on the West Side and North Side. It also means candidates ask harder questions about a hospital's finances than they did three years ago. At the other end of the market, Northwestern Medicine plans a tower of about 1.2 million square feet with more than 200 new inpatient beds on its downtown campus, pending city and state approvals, which will need staff of its own.
The largest systems in the metro, named here as market context only, include Northwestern Medicine, Advocate Health (formed when Advocate Aurora and Atrium Health merged in December 2022), Endeavor Health (NorthShore and Edward-Elmhurst, merged in January 2022) and Rush. For the citywide hiring picture outside healthcare, see our Chicago staffing agency page.